25 years ago I stared at a medical report showing derangement in the citric acid cycle. I had no idea what that was, nor did I know what biochemistry was. I did try to understand, but this video has taken my hand and given me clarity. Thank you.
Thank you! In the end, adding glycolysis to the citric acid cycle, what is the balance of ATP, NADH and FADH produced? What is the total of ATP generated throughout the respiratory chain ?
What I got clear in all that is that some molecules were burned (oxydized), releasing CO2. I have to gain oxygen and expel CO2 by breathing, all the rest probably comes from food, but seemingly not necessarily from lemons, as the idea of citric acid may suggest. Nanoburning stuff by sybiotioc bacteria-like organelles, OK, sounds like it might work... somehow.
Shouldn't the number of molecules of CO2 and H2O generated by the consumption align with a similar reaction of the full combustion of Glucose? Six CO2 molecules and 12 protons should be produced, but only 3 are mentioned.
It's for one cycle and there's only one molecule of pyuruvate but the final product of glycolysis forms 2 molecules for pyruvate therefore if one cycle makes 3 molecules of CO2 the 2 would make 6
Is the citric acid cycle the opposite to TCA cycle? I mean, the one used by Plasmodium Falciparum, as it not follow the usual route to generate ATP. Thank you
@@orbismworldbuilding8428 It completes what the glycolysis did And releases NADH and FADH2 which are then used by the Electron transport chain to produce ATP "the fuel of the human body" There are two videos on the channel for glycolysis and electron transport chain You can watch them for further understanding.
Then how the hell complete oxidation is supposed to happen? It does enter but before starting the Krebs cycle there's another series of steps taking place in the form of a cycle called link/gateway cycle where pyruvate is converted into acetyl Co-A by decarboxylation and dehydrogenation (oxidative decarboxylation) and the enzyme is pyruvate dehydrogenase complex, it does take place in matrix of mitochondria
25 years ago I stared at a medical report showing derangement in the citric acid cycle. I had no idea what that was, nor did I know what biochemistry was. I did try to understand, but this video has taken my hand and given me clarity. Thank you.
"Complex life" may be an understatement
*"Complex life" may become Understandable
divine life, is a better understanding...
"holy shit wtf is happening life" is probably the perfect one
"Complex life" is a fact lol
What the hell. I mean what the hell man.
This is incredible and awe inspiring. It almost makes me mad.
Excellent. Dense content clarified with precision. Many thanks
How the hell am I supposed to remember any of this
Thank you, Mr Omar Ali.
Great presentation as usual. Leading edge.
Your videos have been so helpful! Thank you!
Thank you! In the end, adding glycolysis to the citric acid cycle, what is the balance of ATP, NADH and FADH produced? What is the total of ATP generated throughout the respiratory chain
?
ATP: 3, NADH: 4, FADH2: 1. Total ATP: roughly 32.
Watch Khan Academy for that!
What I got clear in all that is that some molecules were burned (oxydized), releasing CO2. I have to gain oxygen and expel CO2 by breathing, all the rest probably comes from food, but seemingly not necessarily from lemons, as the idea of citric acid may suggest. Nanoburning stuff by sybiotioc bacteria-like organelles, OK, sounds like it might work... somehow.
Great videos, thank you for your effort.
this is mind blowing
more useful than my biochemistry teacher
Thank you
perfect animation
Why there is no energetic summary at the end?
Which carrier protein transport the Pyruvate into the Mitochondrial Matrix Omar Ali
Mitochondrial pyruvate carrier (MPC)
fantastic work... awosome
Amazing! Thanks!
Beautiful
Shouldn't the number of molecules of CO2 and H2O generated by the consumption align with a similar reaction of the full combustion of Glucose? Six CO2 molecules and 12 protons should be produced, but only 3 are mentioned.
He did one cycle using one Pyruvate molecule, remember from glycolysis, one Glucose molecule made two Pyruvates. So you do this twice for your 6 CO2.
It's for one cycle and there's only one molecule of pyuruvate but the final product of glycolysis forms 2 molecules for pyruvate therefore if one cycle makes 3 molecules of CO2 the 2 would make 6
Is the citric acid cycle the opposite to TCA cycle? I mean, the one used by Plasmodium Falciparum, as it not follow the usual route to generate ATP. Thank you
Lara Petrus
Citric Acid Cycle =Tri-Carboxylic Acid Cycle "TCA"
Very helpful sir
thanks
Very cool!
Excellent... thanks 🙏
Why does this guy’s subs not show?
Glycolysis takes place in the cytosol of the cell
same shit with cytoplasm
What does the citric acid cycle do?
@@orbismworldbuilding8428
It completes what the glycolysis did
And releases NADH and FADH2 which are then used by the Electron transport chain to produce ATP "the fuel of the human body"
There are two videos on the channel for glycolysis and electron transport chain
You can watch them for further understanding.
Absolutely no chance that appeared from randomness
Obrigada!!!!!!!!!!!!!!!
You are saying a high school student has to remember all this ?
this is a HARVARD course
Amazing
true
OK, people, now you have to repeat that.
soo complex
you are wrong pryuvate doesn't enter in mitochondria
Then how the hell complete oxidation is supposed to happen? It does enter but before starting the Krebs cycle there's another series of steps taking place in the form of a cycle called link/gateway cycle where pyruvate is converted into acetyl Co-A by decarboxylation and dehydrogenation (oxidative decarboxylation) and the enzyme is pyruvate dehydrogenase complex, it does take place in matrix of mitochondria
@@anubhutimishra422 it occurs in cytoplasm
@@pwh0339 google it, it occurs in mitochondrial matrix.
@@anubhutimishra422 in trueman it is cytoplasm
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